Publications

Hoofdzaken Ambities van het Nationaal Initiatief Hersenen en Cognitie

Nieuwsgierig naar onze ambities? Lees hierover in de uitgave ‘Hoofdzaken – Ambities van het Nationaal Initiatief Hersenen en Cognitie’.

Corporate brochure NIHC

Download voor meer informatie over het NIHC de corporate folder in pdf-formaat.

HCMI Formulier voortgangsrapportage coördinator

HCMI Formulier voortgangsrapportage project

HCMI Formulier voortgangsrapportage coördinator 2011 Engels

HCMI Formulier voortgangsrapportage project 2011 Engels

Overeenkomst VSNU

Regeling subsidieverlening NWO

Imaging the default mode network in aging and dementia

Although in the last decade brain activation in healthy aging and dementia was mainly studied using task- activation fMRI, there is increasing interest in task-induced decreases in brain activity, termed deactivations. These deactivations occur in the so-called default mode network (DMN). In parallel a growing number of studies focused on spontaneous, ongoing ‘baseline’ activity in the DMN. These resting state fMRI studies explored the functional connectivity in the DMN. Here we review whether normal aging and dementia affect task-induced deactivation and functional connectivity in the DMN. The majority of studies show a decreased DMN functional connectivity and task-induced DMN deactivations along a continuum from normal aging to mild cognitive impairment and to Alzheimer's disease (AD). Even subjects at risk for developing AD, either in terms of having amyloid plaques or carrying the APOE4 allele, showed disruptions in the DMN. While fMRI is a useful tool for detecting changes in DMN functional connectivity and deactivation, more work needs to be conducted to conclude whether these measures will become useful as a clinical diagnostic tool in AD. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease.

Bi-national Addiction Workshop, Preliminary programme

Charateristics of effective internet-mediated interventions to change lifestyle in people aged 50 and older; a systematic review

Worldwide, the number of people aged 60 years and older steadily grows to a predicted 2 billion in 2050. Online interventions increasingly target lifestyle risk factors to promote healthy aging. The objective of this systematic review is to evaluate whether Internet mediated lifestyle interventions can successfully change lifestyle in people aged 50 and older. A PubMed search was conducted resulting in twelve articles, based on ten studies. The studies focused on physical activity, weight loss, nutrition, and diabetes. Nine studies used feasible interventions, with an average small to moderate effect size. The most important result is that there are multiple studies reporting positive lifestyle changes in an older population. On average, complex interventions, whether they present tailored or generic information, and online or offline comparison, are more effective than interventions with only one component. Internet mediated interventions hold great potential in implementing effective lifestyle programs, capable of reaching large populations of older persons at very low costs.

Programmaboekje Congres Hersenen en Cognitie: Maatschappelijke Innovatie

Programma van het congres Hersenen en Cognitie: Maatscahppelijke Innovatie op 1 december 2011, inclusief samenvattingen van de gepresenteerde onderzoeksprojecten en demo's.

History of the NIHC

In 2009, the National Initiative Brain & Cognition (NIHC) was founded: an organization with a focus on cognitive neuroscience. The objective of the present study was to explore the prior phase to the founding agreement of the NIHC. This study aimed at giving a clear and concise presentation of the history of the NIHC and the actors that have had an effect on the organization development process, i.e. the policy-making process that preceded the foundation of the NIHC. This report has been written by Anja Kroon as part of her master study “Management Policy Analysis and Entrepreneurship in health and life sciences”, followed at the Vrije Universiteit (VU).

Maatschappelijke waardecreatie binnen het domein Hersenen & Cognitie

Studie door Technopolis Group in opdracht van het Nationaal Initiatief Hersenen & Cognitie. (November 2011)

Programme The non-conscious mind

Programma bijeenkomst 1 februari, The non-conscious mind.

International symposium on PET and SPECT in Neurology and Psychiatry